Pharmacology & Toxicology Faculty
Dr. Xu Photo
Hui Xu, AssistantProfessor
1983, MD, Medicine, Xinjiang Medical University/China
1999, PhD, Kagawa Medical University/Japan
2000, Visiting Scientist, Anesthesiology, University of Arkansas Medical School
2000-2005, Visiting Research Associate (with Dr. J. Galligan), Michigan State University
2005-present, Assistant Professor, Pharmacology & Toxicology, Michigan State University
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Selected Achievements Since 2001

American Heart Association Postdoctoral Fellowship – 2003-2005 (covers stipend and health insurance only)

Young Scientist Travel Award Recipient for the Experimental Biology Meeting ’04, Washington, DC

Selected Publications/Abstracts since joining Dr. Galligan

Xu H, Fink GD, Galligan JJ: ET-1 induced elevations in blood pressure are independent of increases in sympathetic nerve activity in normotensive rats. FASEB J. 15(4): A230, 2001. (Abstract)

Xu H, Fink GD, Chen A, Watts SW, Galligan JJ: Nitric oxide-independent effects of tempol on sympathetic nerve activity and blood pressure in normotensive rats. Hypertension 38(3): P114, p. 510, 2001. (Abstract)

Xu H, Fink GD, Chen A, Watts SW, Galligan JJ: Nitric oxide-independent effects of tempol on sympathetic nerve activity and blood pressure in normotensive rats. Amer. J. Physiol. 281(2): H975-H980, 2001.

Xu H, Fink GD, Galligan JJ: Endothelin-1-induced elevation in blood pressure is independent of increases in sympathetic nerve activity in normotensive rats. J. Cardiovasc. Pharmacol. 38(5): 784-795, 2001.

Xu H, Fink GD, Watts SW, Chen A, Rech R, Galligan JJ: Nitric oxide-dependent and –independent effects of tempol on renal sympathetic nerve activity and blood pressure in deoxycorticosterone acetate (DOCA)-salt hypertensive rats. Soc. Neurosci. Abstr. 27: A242.9, 2001. (Abstract)

Xu H, Fink GD, Galligan JJ: Nitric oxide-dependent and –independent effects of tempol on renal sympathetic nerve activity an blood pressure in deoxycorticosterone acetate (DOCA)-hypertensive rats. Amer. J. Physiol. 283(3): H885-H892, 2002.

Li L, Xu H, Watts SW, Galligan JJ, Fink GD, Chen AF: ET-1 augments venous contractility via NADPH oxidase-induced superoxide in DOCA-salt hypertension. FASEB J. 16(5 Pt 2): p. 1135, 2002. (Abstract)

Fink GD, Watts SW, Chen A, Xu H, Galligan JJ: Superoxide anion contributes to hypertension during inhibition of nitric oxide synthesis. Hypertension 40(3): A7, p. 380, 2002. (Abstract)

Fink GD, Xu H, Galligan JJ: a1-Adrenergic receptors contribute to norepinephrine-induced increases in heart rate in mice. Hypertension 40(3): P65, p. 406, 2002. (Abstract)

Xu H, Fink GD, Galligan JJ: Intra-duodenal administration of tempol lowers blood pressure and inhibits sympathetic nerve activity normotensive and DOCA-salt hypertensive rats. FASEB J. 17(4 Pt 1): #576.5, p. A886, 2003. (Abstract)
Xu H, Fink GD, Galligan JJ: Superoxide independent effects of tempol on blood pressure and sympathetic nerve activity in DOCA-salt hypertensive rats. Hypertension, A57, 2003. (Abstract)

Xu H, Fink GD, Galligan JJ: Tempol lowers blood pressure and sympathetic nerve activity but not vascular O2- in DOCA-salt rats. Hypertension 43(2): 329-334, 2004.

Xu H, Fink GD, Galligan JJ: Increased sympathetic venoconstriction and reactivity to norepinephrine in mesenteric veins in anesthetized DOCA-salt hypertensive rats. Hypertension 44: P48, 2004. (Abstract)

Xu H, Watts SW, Rondelli CM, Fink GD, Galligan JJ. Tempol activates BK channels to cause mesenteric arterial vasodilation in normotensive and deoxycorticosterone acetate (DOCA)-salt hypertensive rats. FASEB J. 19:(4pt1) (Abstract), A703.10, 2005. (Abstract)

Wang H, Xu H, Fink GD, Galligan JJ. Decreased distensibility and myogenic tone in mesenteric veins from DOCA-salt hypertensive rats. Hypertension, 46: (P131, Abstract)

Taylor M, Xu H, Watts SW, Galligan JJ. Contribution of L-type Ca2+ channels to KCl-induced constriction of mesenteric arteries and veins from normotensive and DOCA-salt hypertensive rats. Hypertension, 46: 10 (P117, Abstract)

Xu H, Bian X, Watts SW, Hlavacova A, Fink GD, Galligan JJ. Activation of vascular BK channels by tempol in DOCA-salt hypertensive rats. Hypertension, 46: 10 (P121, Abstract)

Xu H, Bian X, Watts SW, Hlavacova A. Activation of Vascular BK Channel by Tempol in DOCA-salt Hypertensive Rats. Hypertension, 2005; 46: (In press).

Xu H, Bian X, Watts SW, Hlavacova A. Activation of vascular BK channel in DOCA-salt hypertension. Hypertension 44: 1154 ­ 1162, 2005.

Xu H, Wang H, Fink GD, Galligan JJ. Contribution of L-type Ca2+ channels to constriction of mesenteric arteries and veins in DOCA-salt hypertensive rats. FASEB A, 890, 2006

Xu H, Jackson WF, Fink GD, Galligan JJ. Activation of BK Channels by Tempol in Arterial Smooth Muscle Cells from Normotensive and DOCA-salt Hypertensive Rats. Hypertension, 48, 2006 (In press)