Jamie Bernard, PhD
Associate Professor and Ph.D. Program Director
Pharmacology & Toxicology
Pharmacology & Toxicology
Lab Staff
Lab Postdocs
Colleges
Associations
- Division of Dermatology
Programs
Sections
- PHM 910 Seminar (in-person) - Fall
- PHM 899 Master's Thesis Research (in-person) - Fall
- PHM 802 Cellular, Molecular and Integrated Systems Pharmacology (in-person) - Spring
- PHM 899 Master's Thesis Research (in-person) - Spring
- PHM 910 Seminar (in-person) - Spring
- PHM 899 Master's Thesis Research (in-person) - Summer
Works
- Adipocyte-derived kynurenine stimulates malignant transformation of mammary epithelial cells through the aryl hydrocarbon receptor. Biochemical Pharmacology (2023)
- The Tumor Promotional Role of Adipocytes in the Breast Cancer Microenvironment and Macroenvironment. The American Journal of Pathology (2021)
- Photoimmunology: how ultraviolet radiation affects the immune system. Nature Reviews Immunology (2019-11-18)
- Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay. Scientific reports (2019-07-16)
- Identifying chemopreventive agents for obesity-associated cancers using an efficient, 3D high-throughput transformation assay. Scientific Reports (2019-07-16)
- Lipectomizing Mice for Applications in Metabolism. Methods in molecular biology (Clifton, N.J.) (2019-01-01)
- Lipectomizing mice for applications in metabolism. Methods in Molecular Biology (2019)
- A role for FGF2 in visceral adiposity-associated mammary epithelial transformation. Adipocyte (2018-03-21)
- A role for FGF2 in visceral adiposity-associated mammary epithelial transformation. Adipocyte (2018)
- Why does a high-fat diet increase cancer risk?. Future oncology (London, England) (2018-02-07)
- A BET Bromodomain Inhibitor Suppresses Adiposity-Associated Malignant Transformation. Cancer prevention research (Philadelphia, Pa.) (2017-12-15)
- A BET bromodomain inhibitor suppresses adiposity-associated malignant transformation. Cancer Prevention Research (2018)
- Elucidating the role of adipose tissue secreted factors in malignant transformation. Adipocyte (2017-11-02)
- Elucidating the role of adipose tissue secreted factors in malignant transformation. Adipocyte (2018)
- Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer. Oncogene (2017-08-07)
- Fibroblast growth factor receptor is a mechanistic link between visceral adiposity and cancer. Oncogene (2017)
- Deciphering metabolic rewiring in breast cancer subtypes. Translational research : the journal of laboratory and clinical medicine (2017-07-15)
- Deciphering metabolic rewiring in breast cancer subtypes. Translational Research (2017)
- PDE2 is a novel target for attenuating tumor formation in a mouse model of UVB-induced skin carcinogenesis. PloS one (2014-10-16)
- PDE2 is a novel target for attenuating tumor formation in a mouse model of UVB-induced skin carcinogenesis. PLoS ONE (2014)
- Toll-like receptor 3 activation is required for normal skin barrier repair following UV damage. The Journal of investigative dermatology (2014-08-12)
- Toll-like receptor 3 activation is required for normal skin barrier repair following UV damage. Journal of Investigative Dermatology (2015)
- Parametrial fat tissue from high fat diet-treated SKH-1 mice stimulates transformation of mouse epidermal JB6 cells. Journal of carcinogenesis & mutagenesis (2014-07-01)
- Innate immune sensors stimulate inflammatory and immunosuppressive responses to UVB radiation. The Journal of investigative dermatology (2014-06-01)
- Innate immune sensors stimulate inflammatory and immunosuppressive responses to UVB radiation. Journal of Investigative Dermatology (2014)
- Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice. Experimental and molecular pathology (2013-10-30)
- Inverse relationship between p53 and phospho-Chk1 (Ser317) protein expression in UVB-induced skin tumors in SKH-1 mice. Experimental and Molecular Pathology (2014)
- Oral caffeine during voluntary exercise markedly inhibits skin carcinogenesis and decreases inflammatory cytokines in UVB-treated mice. Nutrition and cancer (2013-09-26)
- Oral caffeine during voluntary exercise markedly inhibits skin carcinogenesis and decreases inflammatory cytokines in UVB-treated mice. Nutrition and Cancer (2013)
- Inhibition of UVB-induced nonmelanoma skin cancer: a path from tea to caffeine to exercise to decreased tissue fat. Topics in current chemistry (2013-01-01)
- Inhibition of UVB-induced nonmelanoma skin cancer: A path from tea to caffeine to exercise to decreased tissue fat. Topics in Current Chemistry (2013)
- Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nature medicine (2012-07-08)
- Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nature Medicine (2012)
- Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet. Proceedings of the National Academy of Sciences of the United States of America (2012-05-21)
- Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet. Proceedings of the National Academy of Sciences of the United States of America (2012)
- Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptides. Journal of immunology (Baltimore, Md. : 1950) (2011-12-02)
- Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptides. Journal of Immunology (2012)
- Protecting the boundary: the sentinel role of host defense peptides in the skin. Cellular and molecular life sciences : CMLS (2011-05-15)
- Protecting the boundary: The sentinel role of host defense peptides in the skin. Cellular and Molecular Life Sciences (2011)
- The Feverfew plant-derived compound, parthenolide enhances platelet production and attenuates platelet activation through NF-κB inhibition. Thrombosis research (2011-01-26)
- The Feverfew plant-derived compound, parthenolide enhances platelet production and attenuates platelet activation through NF-κB inhibition. Thrombosis Research (2011)
- Cyclooxygenase-2 enhances antimicrobial peptide expression and killing of Staphylococcus aureus. Journal of immunology (Baltimore, Md. : 1950) (2010-10-22)
- Cyclooxygenase-2 enhances antimicrobial peptide expression and killing of staphylococcus aureus. Journal of Immunology (2010)
- Foxp3 regulates megakaryopoiesis and platelet function. Arteriosclerosis, thrombosis, and vascular biology (2009-08-06)
- Foxp3 regulates megakaryopoiesis and platelet function. Arteriosclerosis, Thrombosis, and Vascular Biology (2009)
- 15-deoxy-Delta12,14 prostaglandin J2-induced heme oxygenase-1 in megakaryocytes regulates thrombopoiesis. Journal of thrombosis and haemostasis : JTH (2008-10-10)
-
15-deoxy-Δ12,14 prostaglandin J
2 -induced heme oxygenase-1 in megakaryocytes regulates thrombopoiesis. Journal of Thrombosis and Haemostasis (2009) - 15-deoxy-delta12,14-PGJ2 enhances platelet production from megakaryocytes. Blood (2008-08-28)
- 15-deoxy-{Delta}12,14-PGJ2 enhances platelet production from megakaryocytes. Blood (2008)
- Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles. Thrombosis and haemostasis (2008-01-01)
- Peroxisome proliferator-activated receptor γ and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles. Thrombosis and Haemostasis (2008)
- The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects. PPAR research (2008-01-01)
- The platelet as a therapeutic target for treating vascular diseases and the role of eicosanoid and synthetic PPARgamma ligands. Prostaglandins & other lipid mediators (2006-07-10)
- The platelet as a therapeutic target for treating vascular diseases and the role of eicosanoid and synthetic PPARγ ligands. Prostaglandins and Other Lipid Mediators (2007)
- Platelets as a novel target for PPARgamma ligands : implications for inflammation, diabetes, and cardiovascular disease. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy (2006-01-01)
- Platelets as a novel target for PPARγ ligands: Implications for inflammation, diabetes, and cardiovascular disease. BioDrugs (2006)